Studies have shown DMG can improve the immune response by potentiating both cell-mediated and humoral (antibody) Research suggests that DMG may in fact be beneficial for these conditions, although the actual benefit for these conditions is unproven through controlled studies. Holistic veterinarians have also recommended DMG as a supplement for pets with seizures and allergies. DMG is considered an anti-stress nutrient. Many doctors prescribe it for horses, dogs, and cats to improve performance and enhance recovery from various health problems. Its mechanism in the treatment of osteoarthritis is via an anti-inflammatory effect. It has been recommended for use in pets with a variety of conditions including osteoarthritis at a dose of 50 to 500 mg per day. DMG appears to enhance oxygen usage, prevent the accumulation of lactic acid, improve muscle metabolism, function as an anti-stress nutrient to improve the cardiovascular system, and reduce recovery time after vigorous physical activity. Increased dietary intake of DMG is to provide carbon to cells.
Both the human and animal body makes DMG from choline and betaine. It is found in low levels in foods, including meats, seeds, and grains. DMG stands for dimethylglycine, also called vitamin B15.